I am honored by this invitation in being the guest of your Academy at this Annual Congress and doubly honored to have been asked to deliver this first Paul A. O'Leary Memorial Lecture. American dermatology is about a hundred years old. It stemmed from the solid and scientific foundations of the Austrian and German schools, the artistic logic and the imaginative genius of France, and from the careful clinical observations and the experience of the dermatological men of Britain. The American school has achieved a valuable and scholarly synthesis of these national traits and has steadily grown in strength. Some of your early masters have long been household names in dermatology—White, Duhring, Bulkley, Fox, Fordyce—but in the last quarter of the century American dermatology has forged ahead and is now in the vanguard. We turn to watch your signals; we seek to visit your camps and to