Nicotine potentiation of haloperidol in reducing tic frequency in Tourette's disorder [published erratum appears in Am J Psychiatry 1991 Sep;148(9):1282]
- 1 June 1991
- journal article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 148 (6), 793-794
- https://doi.org/10.1176/ajp.148.6.793
Abstract
In an open, nonblind study, 10 patients with Tourette's disorder who were being treated with haloperidol were videotaped before, while, and after chewing nicotine gum. The frequency of tics was reduced significantly during the 30-minute gum-chewing period and during the 1 hour after gum chewing. Nicotine appears to potentiate haloperidol effects in patients with Tourette's disorder.Keywords
This publication has 7 references indexed in Scilit:
- Fluoxetine Treatment of Children and Adolescents with Tourette's and Obsessive Compulsive Disorders: Preliminary Clinical ExperienceJournal of the American Academy of Child & Adolescent Psychiatry, 1990
- NICOTINE AND TOURETTE'S SYNDROMEThe Lancet, 1989
- The Yale Global Tic Severity Scale: Initial Testing of a Clinician-Rated Scale of Tic SeverityJournal of the American Academy of Child & Adolescent Psychiatry, 1989
- Nicotine potentiates the effects of haloperidol in animals and in patients with Tourette syndromeBiomedicine & Pharmacotherapy, 1989
- NICOTINE GUM AND HALOPERIDOL IN TOURETTE'S SYNDROMEThe Lancet, 1988
- The natural history of Tourette syndrome: A follow‐up studyAnnals of Neurology, 1987
- ON THE METHODS AND THEORY OF RELIABILITYJournal of Nervous & Mental Disease, 1976