Sirt1 Regulates Aging and Resistance to Oxidative Stress in the Heart
Top Cited Papers
Open Access
- 25 May 2007
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 100 (10), 1512-1521
- https://doi.org/10.1161/01.res.0000267723.65696.4a
Abstract
Silent information regulator (Sir)2, a class III histone deacetylase, mediates lifespan extension in model organisms and prevents apoptosis in mammalian cells. However, beneficial functions of Sir2...Keywords
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