High-Risk Surgical Acute Renal Failure Treated by Continuous Arteriovenous Hemodiafiltration: Metabolic Control and Outcome in Sixty Patients

Abstract

The outcome and metabolic control was studied in 60 critically ill patients with acute renal failure (ARF) treated by continuous arteriovenous hemodiafiltration (CAVHD) in a single surgical intensive care unit. Mean age ( ± SEM) was 60 ± 2 years with a male predominance (80%). The majority of patients required mechanical ventilation (83%) and/or vasopressor support (70%) and suffered from multiorgan failure [mean number of organ system failures 3.3 ± 0.3 (range 1-6)]. CAVHD resulted in a rapid decline of serum urea and creatinine levels during the first 72 h (urea 47.4 ± 2.3 to 30.3 ± 1.4 mmol/l, p -₃