Estrogen and Progestin, Lipoprotein(a), and the Risk of Recurrent Coronary Heart Disease Events After Menopause
Open Access
- 12 April 2000
- journal article
- clinical trial
- Published by American Medical Association (AMA) in JAMA
- Vol. 283 (14), 1845-1852
- https://doi.org/10.1001/jama.283.14.1845
Abstract
Lipoprotein(a) [Lp(a)] has been found to be an independent risk factor for coronary heart disease (CHD) events in most1-7 but not all8-10 prospective studies of men without known coronary artery disease. Few prospective studies have evaluated the importance of Lp(a) as a risk factor among women or among persons with CHD.11 Furthermore, it is unknown whether interventions directed at lowering Lp(a) levels will affect subsequent risk of CHD. Lipoprotein(a) levels are not lowered by most lipid-lowering medications, diet, or exercise.12,13 Among standard lipid-lowering therapies, only nicotinic acid has been shown to reduce Lp(a) levels.14-18Keywords
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