Assignment of human ?-galactosidase-A gene to 3p21.33 by fluorescence in situ hybridization
- 1 October 1993
- journal article
- Published by Springer Nature in Human Genetics
- Vol. 92 (4), 403-404
- https://doi.org/10.1007/bf01247344
Abstract
GM1 gangliosidosis and Morquio syndrome type B (MPS IVB) are inherited lyosomal storage disorders associated with deficiency of β-galactosidase-A (βGALA) activity. A recombinant plasmid containing a biotinylated cDNA (2.4-kb insert) encoding human β GALA was used to localize the enzyme locus by fluorescence in situ hybridization (FISH). The human β GALA gene was assigned to 3p21.33 by FISH.Keywords
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