Inhibition of sterol biosynthesis in animal cells by 14 alpha-alkyl-substituted 15-oxygenated sterols.
Open Access
- 1 November 1979
- journal article
- research article
- Published by Elsevier in Journal of Lipid Research
- Vol. 20 (8), 994-998
- https://doi.org/10.1016/s0022-2275(20)40001-x
Abstract
No abstract availableThis publication has 18 references indexed in Scilit:
- Inhibitors of sterol biosynthesis. Syntheses of 14α-alkyl substituted 15-oxygenated sterolsChemistry and Physics of Lipids, 1979
- Inactive 3-hydroxy-3-methylglutaryl-coenzyme a reductase in broken cell preparations of various mammalian tissues and cell culturesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1979
- Sterol synthesis. Chemical synthesis, structure determination and metabolism of 14?-methyl-5?-cholest-7-en-3?, 15?-diol and 14?-methyl-5?-cholest-7-en-3?, 15?-diolChemistry and Physics of Lipids, 1978
- Inhibition of sterol synthesis in L cells by 14α-ethyl-5α-cholest-7-en-15α-ol-3-one at nanomolar concentrationsBiochemical and Biophysical Research Communications, 1977
- Inhibitors of sterol synthesis. Hypocholesterolemic action of dietary 5α-cholest-8(14)-en-3β-ol-15-one in rats and miceBiochemical and Biophysical Research Communications, 1977
- 14.alpha.-Ethyl-5.alpha.-cholest-7-ene-3.beta.,15.alpha.-diol, an extraordinarily potent inhibitor of sterol biosynthesis in animal cellsJournal of the American Chemical Society, 1977
- Inhibition of hepatic sterol synthesis and reduction of serum cholesterol in rats by 5α-cholest-8(14)-en-3β-ol-15-oneBiochemical and Biophysical Research Communications, 1976
- Cholesterol, 7-ketocholesterol and 25-hydroxycholesterol uptake studies and effect on 3-hydroxy-3-methylglutaryl-coenzyme a reductase activity in human fibroblastsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1975
- Inhibition of cell growth by oxygenated derivatives of cholesterolNature, 1974
- Enzymatic conversion of 14α-methyl-cholest-7-en-3β,15ξ-diol to cholesterolBiochemical and Biophysical Research Communications, 1970