Abstract
A study of the sensitivity of the blood sugar response to injected insulin in a series of 20 normal [male] [male] and of 93 mentally disturbed soldiers revealed that the mean maximum level of hypoglycemia (in 30 mins.) was 29.6 mg./hundred cc. in the former and 41.4 mg./hundred cc. in the latter. This difference in reactivity was statistically significant. Forty-six % of the patients showed a less pronounced drop in blood sugar than any of the normal subjects. The secondary rise in blood sugar following the hypoglycemia was the same in the 2 groups. This resistiveness to insulin was noted with all clinical types of mental disturbance and is probably indicative of a coincidental change in the reactivity of the endocrine factors controlling the regulation of blood sugar.