Progesterone stimulates energy-dependent contraction of swollen heart mitochondria
- 1 March 1981
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 37 (3), 237-238
- https://doi.org/10.1007/bf01991629
Abstract
Summary Progesterone stimulates the rate and efficiency of respiration-dependent contraction of heart mitochondria in nitrate salts at alkaline pH. Ion extrusion under these conditions is normally slow and inefficient due to the elevated permeability of the membrane to monovalent cations through a putative uniport pathway. Progesterone also inhibits passive swelling under these conditions and appears to act by restricting cation influx through the uniport pathway.Keywords
This publication has 14 references indexed in Scilit:
- N,N'-Dicyclohexylcarbodiimide inhibits monovalent cation influx but not cation/proton exchange in heart mitochondria.Journal of Biological Chemistry, 1980
- Energy-Dependent contraction of swollen heart mitochondria—Activation by butacaineArchives of Biochemistry and Biophysics, 1979
- Ion Transport by MitochondriaPublished by Springer Nature ,1978
- Energy-dependent exchange of K+ in heart mitochondria K+ influxArchives of Biochemistry and Biophysics, 1977
- Effect of Progesterone on Respiration and Oxidative PhosphorylationEuropean Journal of Biochemistry, 1972
- Inhibition of mitochondrial swelling by 19-nor-ethynyltestosterone acetate and other steroidsArchives of Biochemistry and Biophysics, 1971
- Inhibition of mitochondrial respiration by progesterone and an azasteroidArchives of Biochemistry and Biophysics, 1967
- Site-specific effects of steroids on mitochondrial metabolismBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1967
- STEROIDS AND CELL SURFACESBiological Reviews, 1961
- The mechanism of action of hydrocortisone on mitochondrial metabolismBiochemical Journal, 1960