Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene.
- 1 October 1986
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 83 (19), 7226-7230
- https://doi.org/10.1073/pnas.83.19.7226
Abstract
A genomic phage clone containing a full-length copy of a functional human gene for ferritin heavy chain has been isolated. The gene consists of four exons spanning approximately 3 kilobases and has been localized to chromosome 11. The functionality of the gene was demonstrated by the fact that both transient transfectants and stable transformants of murine fibroblasts actively transcribe human ferritin heavy-chain mRNA.Keywords
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