Cloning and structure of cDNA encoding α‐latrotoxin from black widow spider venom
- 17 September 1990
- journal article
- Published by Wiley in FEBS Letters
- Vol. 270 (1-2), 127-131
- https://doi.org/10.1016/0014-5793(90)81250-r
Abstract
CDNA encoding the putative alpha-latrotoxin precursor was isolated from spider venom glands cDNA library and sequenced. The cDNA contained the 4203 base-pair open reading frame corresponding to the 156,855-Da protein composed of 1401 amino acids. Computer analysis of the deduced primary structure revealed the presence of various internal imperfect repeats mainly in its central and C-terminal regions.Keywords
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