The Development of Neurogenic Vesical Dysfunction after Experimental Spinal Cord Injury or Sacral Rhizotomy in Non-Human Primates

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Abstract
Vesical and urethral function were studied urodynamically before and after spinal cord or sacral root injury in nonhuman primates [crab eater monkeys]. Detrusor sphincter discoordination developed in animals with complete suprasacral spinal cord injury. Animals subjected to complete intradural sacral rhizotomy developed hypertonic areflexic vesical dysfunction while those subjected to dorsal root ganglionectomy developed a high compliance low pressure bladder.