Identification of an Amplified, Highly Expressed Gene in a Human Glioma
- 3 April 1987
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 236 (4797), 70-73
- https://doi.org/10.1126/science.3563490
Abstract
A gene, termed gli, was identified that is amplified more than 50-fold in a malignant glioma. The gene is expressed at high levels in the original tumor and its derived cell line and is located at chromosome 12 position (q13 to q14.3). The gli gene is a member of a select group of cellular genes that are genetically altered in primary human tumors.This publication has 39 references indexed in Scilit:
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