Serology and Genetics of an MNSs‐Associated Antigen Dantu
- 1 June 1984
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 46 (6), 377-386
- https://doi.org/10.1111/j.1423-0410.1984.tb00102.x
Abstract
Dantu, a previously undescribed low‐incidence red cell antigen, is inherited as a Mendelian dominant character. The Dantu antigen is associated with very weak s antigen, protease resistant N antigen and either very weak or no U antigen. Two of the propositi had previously been shown to have an unusual hybrid MNSs sialoglycoprotein, and it is probably this which carries these unusual N, s and U antigens as well as the Dantu antigen. A study of the family of one propositus suggests, by conventional genetics, that Dantu is not controlled by the MNSs locus; a possible explanation is given. Several examples of anti‐Dantu are known, one was found to cause a positive direct antiglobulin reaction on neonatal red cells.This publication has 10 references indexed in Scilit:
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