Development of a Virtual Screening Method for Identification of “Frequent Hitters” in Compound Libraries
- 4 December 2001
- journal article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 45 (1), 137-142
- https://doi.org/10.1021/jm010934d
Abstract
Read the full review for this F1000Prime recommended article: Development of a virtual screening method for identification ofKeywords
This publication has 18 references indexed in Scilit:
- Prediction of Hepatic Metabolic ClearanceClinical Pharmacokinetics, 2001
- Improving the Odds in Discriminating “Drug-like” from “Non Drug-like” CompoundsJournal of Chemical Information and Computer Sciences, 2000
- LeadScope: Software for Exploring Large Sets of Screening DataJournal of Chemical Information and Computer Sciences, 2000
- Computational methods for the prediction of ‘drug-likeness’Drug Discovery Today, 2000
- The Design of Leadlike Combinatorial LibrariesAngewandte Chemie International Edition, 1999
- A Scoring Scheme for Discriminating between Drugs and NondrugsJournal of Medicinal Chemistry, 1998
- Can We Learn To Distinguish between “Drug-like” and “Nondrug-like” Molecules?Journal of Medicinal Chemistry, 1998
- Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settingsAdvanced Drug Delivery Reviews, 1997
- Atomic physicochemical parameters for three dimensional structure directed quantitative structure-activity relationships. 4. Additional parameters for hydrophobic and dispersive interactions and their application for an automated superposition of certain naturally occurring nucleoside antibioticsJournal of Chemical Information and Computer Sciences, 1989
- Self-organized formation of topologically correct feature mapsBiological Cybernetics, 1982