REDUCTION OF POLYPHARMACY FOR EPILEPSY IN AN INSTITUTION FOR THE RETARDED

Abstract

It is a well-established fact that 20-40% of patients in residential institutions for the retarded have seizures and take anticonvulsants. Most patients have quiescent seizure disorders and can manage well on monotherapy. In this study, 78% of the patients remained seizure-free after switching from multiple-drug regimens to monotherapy.