Immunologic Reactions in Trichinosis with Purified Antigens

Abstract

Intradermal, precipitin and complement-fixation tests were performed on 120 individuals 12 weeks after the onset of symptoms of trichinosis. For this purpose, an alkaline saline extract, an acid soluble protein and a polysaccharide were utilized. Although highly concentrated, these fractions were found to be less sensitive than the crude extracts of Trichinella spiralis commonly em -ployed. The serologically active substance or substances were heat stable and precipitable by alcohol and acetone. As a result of these studies, a practical method of standardizing reagents for serologic tests in trichinosis is formulated.