Frequency of deletion of short arm satellites in acrocentric chromosomes
Open Access
- 1 June 1974
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 11 (2), 177-180
- https://doi.org/10.1136/jmg.11.2.177
Abstract
The frequency of deletion of short arm satellites has been examined in various populations. Four out of 2509 males in psychiatric institutions and prisons had Dps- or Gps- (1·6 per 1000), and five out of 6187 persons in the general population had Dps- or Gps- (0·8 per 1000). The difference is not significant. The segregation rate of the chromosome with lack of short arm satellite material did not deviate from unity in the few families where such calculations were possible. There was no increase in abortions or non-disjunction in the families with an acrocentric chromosome lacking short arm satellite material. The study indicates that the frequency of Dps- and Gps- in the population is between 0·5 and 1·0 per 1000 and that the lack of short arm satellite material is without any deleterious effect on phenotype.Keywords
This publication has 12 references indexed in Scilit:
- Chromosome studies in a neonatal population.1972
- Group G deletion syndromes.Journal of Medical Genetics, 1971
- The G deletion syndromesThe Journal of Pediatrics, 1970
- Familial occurrence of a short arm deletion of a G-group chromosome.1969
- Familial Deletion of the Short Arm of the D1-Chromosome (46, XX, 13 p-) Not Associated with Loss of Haptoglobin or Catalase ActivityClinical Pediatrics, 1969
- Exclusion of marker genes from the short arm of the human chromosome D1 by deletion mapping.1969
- Haptoglobin: a locus on the D1 chromosome?1967
- Atypical acrocentric chromosomes in Negro and Caucasian Mongols.1967
- UNILATERAL FIXATION OF OSSICULAR CHAIN ASSOCIATED WITH G-GROUP CHROMOSOME DELETION1967
- [Deletion of the short arm of a 13-15 chromosome, hypertelorism and Hp0 haptoglobin phenotype in the same family].1966