Over 95% Sensitization against Allogeneic Leukocytes Following Single Massive Blood Transfusion1
- 1 January 1975
- journal article
- Published by Wiley in Vox Sanguinis
- Vol. 28 (1), 66-73
- https://doi.org/10.1111/j.1423-0410.1975.tb02743.x
Abstract
The development and persistence of leukoagglutinating and lymphocytotoxic alloantibodies were systematically studied in 54 patients who had received single massive blood transfusions because of open-heart surgery. Of these patients over 95% were sensitized when tested for both leukoagglutinins and lymphocytotoxins, whereas 74% were found to be immunized when searched for cytotoxic antibodies only. The optimal time for detecting antibodies was 2 weeks after blood transfusions.Keywords
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