Sequence homology between purple acid phosphatases and phosphoprotein phosphatases
- 24 April 1990
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 263 (2), 265-268
- https://doi.org/10.1016/0014-5793(90)81389-6
Abstract
The amino acid sequences of mammalian purple acid phosphatases and phosphoprotein phosphatases are shown to possess regions of significant homology. The conserved residues contain a high percentage of possible metal-binding residues. The phosphoprotein phosphatases 1, 2A and 2B are proposed to be iron-zinc metalloenzymes with active sites isostructural (or nearly so) with those of the purple phosphatases.Keywords
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