Oral Administration of Liposome-entrapped Cysteamine and the Distribution Pattern in Blood, Liver and Spleen
- 1 January 1985
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 47 (6), 615-619
- https://doi.org/10.1080/09553008514550851
Abstract
Oral administration of liposome-entrapped cysteamine induces an increase in the concentration of exogenous sulfur compounds in blood (plasma), liver and spleen. Among those sulfur compounds, an important amount of plasma thiols can be related to a protection of cysteamine in the digestive tract. This can account for the radioprotective effect of a liposomal-cysteamine suspension in rodents, and clearly demonstrates the interest of such a preparation in radioprotection.This publication has 13 references indexed in Scilit:
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