Untersuchungen über den Einfluß von Sulfhydrylreagenzien auf die Acetylcholinesterase
- 1 January 1953
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 295 (Jahresband), 264-270
- https://doi.org/10.1515/bchm2.1953.295.1.264
Abstract
Acetylcholinesterase (AChE) obtained by kieselguhr absorption is not inhibited by K-ferricyanide (10 [image]), o-iodosobenzoate (10-2), or monoiodacetate (10-2) up to 60 min. Mercaptide forming substances as p-chloromercuribenzoate, Naseleneit or Na tellurite are without any effect. Inhibition by Na arsenite or Mapharsen can be reversed by washing or dialysis, or prevented by higher substrate concentration. Inhibition by arsenite prevents inacti-vation by certain alkylphosphates.Keywords
This publication has 7 references indexed in Scilit:
- ACETYLCHOLINESTERASE .11. REVERSIBILITY OF TETRAETHYL PYROPHOSPHATE INHIBITION1951
- Thiol Groups of Biological ImportancePublished by Wiley ,1951
- The Enzymic Hydrolysis and Synthesis of AcetylcholinePublished by Wiley ,1951
- The esterases of horse blood. 2. The specificity of horse erythrocyte cholinesteraseBiochemical Journal, 1950
- ACETYLCHOLINESTERASE .10. MECHANISM OF THE CATALYSIS OF ACYLATION REACTIONS1950
- Dioximaleic Acid Oxidase Action of PeroxidasesNature, 1940
- The Determination of Enzyme Dissociation ConstantsJournal of the American Chemical Society, 1934