Abstract
Firstly, may I say what great pleasure it gives me to have been invited to contribute to this issue of the Annals of Tropical Medicine and Parasitology commemorating Brian Maegraith's 80th birthday. If there is one tropical disease that invariably excites emotional, and sometimes even unnecessarily acrimonious, correspondence, it is malaria. I have nonetheless decided to express my personal views based on an experience of over 30 years on three facets of the disease—chemotherapy, management and chemoprophylaxis—and to review the situation as I see it.