Nucleotide Sequence of the p21 Transforming Protein of Harvey Murine Sarcoma Virus
- 3 September 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 217 (4563), 934-936
- https://doi.org/10.1126/science.6287572
Abstract
Harvey murine sarcoma virus is a retrovirus which transforms cells by means of a single virally encoded protein called p21 has. We have determined the nucleotide sequence of 1.0 kilobase in the 5' half of the viral genome which encompasses the has coding sequences and its associated regulatory signals. The nucleotide sequence has identified the amino acid sequence of two additional overlapping polypeptides which share their reading frames and the carboxyl termini with p21 but which contain additional NH2-terminal amino acids.This publication has 17 references indexed in Scilit:
- Nucleotide Sequence of the Oncogene Encoding the p21 Transforming Protein of Kirsten Murine Sarcoma VirusScience, 1982
- EditorialAdvances in Nursing Science, 1982
- SV40 recombinant molecules express the gene encoding p21 transforming protein of Harvey murine sarcoma virusNature, 1981
- The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genesNature, 1981
- Transcriptional control regions of the adenovirus VAI RNA geneCell, 1980
- Identification of a normal vertebrate cell protein related to the p21 src of harvey murine sarcoma virusVirology, 1980
- Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virusNature, 1980
- A control region in the center of the 5S RNA gene directs specific initiation of transcription: II. The 3′ border of the regionCell, 1980
- Identification of a sarcoma virus-coded phosphoprotein in nonproducer cells transformed by Kirsten or Harvey murine sarcoma virusVirology, 1979
- A new method for sequencing DNA.Proceedings of the National Academy of Sciences, 1977