Febrile Thrombopenic Purpura with Hemolytic Anemia and Platelet Thrombosis

Abstract

A CLINICAL syndrome characterized by fever, a rapidly progressing anemia, mild icterus, thrombopenia, Central-nervous-system manifestations and death in a relatively short time was first described by Moschcowitz¹ in 1925. Since that time a limited number of cases that seemed to fit this picture clinically and pathologically in remarkable similarity have appeared in the literature, the outstanding features at autopsy having been the numerous petechial hemorrhages found in the heart, kidneys, liver and brain, which microscopical examination revealed to be due to platelet thrombi. As yet, no definite reason has been given to explain this peculiar sequence of events, which, in . . .