Receptor-Mediated Gene Targeting to Tissues In Vivo Following Intravenous Administration of Pegylated Immunoliposomes
- 1 January 2001
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 18 (8), 1091-1095
- https://doi.org/10.1023/a:1010910523202
Abstract
Purpose. Gene therapy has been limited by the immunogenicity of viral vectors, by the inefficiency of cationic liposomes, and by the rapid degradation in vivofollowing the injection of naked DNA. The...Keywords
This publication has 20 references indexed in Scilit:
- Rapid transferrin efflux from brain to blood across the blood–brain barrierJournal of Neurochemistry, 2001
- Cardiac angiogenesis and gene therapy: a strategy for myocardial revascularizationCurrent Opinion in Cardiology, 1999
- Stabilized plasmid-lipid particles: factors influencing plasmid entrapment and transfection propertiesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1999
- Branched Cationic Peptides for Gene Delivery: Role of Type and Number of Cationic Residues in Formation and in Vitro Activity of DNA PolyplexesHuman Gene Therapy, 1999
- In Vivo Gene Transfer by Intravenous Administration of Stable Cationic Lipid/DNA ComplexPharmaceutical Research, 1997
- Brain drug delivery of small molecules using immunoliposomesProceedings of the National Academy of Sciences, 1996
- A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung.Proceedings of the National Academy of Sciences, 1996
- Cationic Liposome-mediated Intravenous Gene DeliveryJournal of Biological Chemistry, 1995
- Characterization and Distribution of Transferrin Receptors in the Rat BrainJournal of Neurochemistry, 1990
- Targeting Genes: Delivery and Persistent Expression of a Foreign Gene Driven by Mammalian Regulatory Elements in VivoJournal of Biological Chemistry, 1989