Endosomal Proteolysis of Internalized Insulin at the C-terminal Region of the B Chain by Cathepsin D
Open Access
- 1 March 2002
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (11), 9437-9446
- https://doi.org/10.1074/jbc.m110188200
Abstract
No abstract availableKeywords
This publication has 62 references indexed in Scilit:
- Inhibition of Endosomal Insulin-like Growth Factor-I Processing by Cysteine Proteinase Inhibitors Blocks Receptor-mediated FunctionsJournal of Biological Chemistry, 2001
- Identification of Insulin Domains Important for Binding to and Degradation by Endosomal Acidic Insulinase*Endocrinology, 2001
- Negative Regulation of Epidermal Growth Factor Signaling by Selective Proteolytic Mechanisms in the Endosome Mediated by Cathepsin BPublished by Elsevier ,1999
- Uptake and metabolic fate of [HisA8,HisB4,GluB10,HisB27]insulin in rat liver in vivoBiochemical Journal, 1998
- Endosomal proteolysis and MHC class II functionCurrent Opinion in Immunology, 1998
- Endosomal proteolysis of internalized proteinsFEBS Letters, 1996
- Proteolysis of Glucagon within Hepatic Endosomes by Membrane-associated Cathepsins B and DJournal of Biological Chemistry, 1995
- Degradation of insulin in isolated liver endosomes is functionally linked to ATP‐dependent endosomal acidificationEuropean Journal of Biochemistry, 1990
- Extracellular presence of the lysosomal proteinase cathepsin B in rheumatoid synovium and its activity at neutral pHArthritis & Rheumatism, 1984
- Immunofluorescent localization of cathepsins B and D in human fibroblasts.Journal of Histochemistry & Cytochemistry, 1981