Evaluation of coal tar fractions for use in psoriasiform diseases using the mouse tail test
- 29 July 2006
- journal article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 92 (5), 575-579
- https://doi.org/10.1111/j.1365-2133.1975.tb03127.x
Abstract
Mouse tail scale epidermis was used as a model to evaluate anti-parakeratotic activity of tar oil acids (phenols) boiling between 175 and 400 degrees C. Lower boiling phenols seemed to cause more irritation, whereas high boiling phenols caused granular layer induction in formerly parakeratotic skin.Keywords
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