Further investigation on the mode of entry of human rotavirus into cells
- 1 March 1986
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 91 (1-2), 135-144
- https://doi.org/10.1007/bf01316734
Abstract
Entry of the KUN strain of human rotavirus into MA 104 cells was studied by electron microscopy. Double-shelled rotavirus particles attached to the cell membrane, and in the presence of trypsin their nucleic acids were expelled from the virus core into the cytoplasm through radial spaces between the capsomeres and the cell membrane pores formed after their attachment. This mechanism was considered to be analogous to those of phages.Keywords
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