Effect of Para-Aminobenzoic Acid on Fever and Joint Pains of Acute Rheumatic Fever

Abstract

Nine children with acute rheumatic fever were given p-aminobenzoic acid, which appeared to have a definite effect in reducing the fever and relieving the joint pains. The immediate dose was 3-4 g., followed by a maintenance dose at 2-3 hr. intervals of 1-3 g. Alkalis were given to prevent acidosis.