Preparation of leukocyte-poor platelet concentrates from buffy coats by a new type of quadruple bag

Abstract
A new quadruple blood bag system for collection of platelet concentrates is described. The principle modification consists of a smaller (150 ml) buffy coat bag in conjunction with SAG-mannitol for red cell preservation. Platelet yield and function were comparable to conventional techniques, leukocyte contamination was lower (1.7 ± 1.3×107 per unit). The system is recommended for specialized institutions with a high demand of blood components.