Gonadotrophin Levels in Male Rats Following Impairment of Leydig Cell Function by Ethylene Dimethanesulphonate
- 24 April 2009
- journal article
- Published by Hindawi Limited in Andrologia
- Vol. 9 (1), 29-35
- https://doi.org/10.1111/j.1439-0272.1977.tb01255.x
Abstract
The effects of the antispermatogenic compound, ethylene dimethanesulphonate on anterior pituitary and serum FSH, LH and prolactin levels in male rats were investigated. A rapid and sustained rise in serum LH, reaching castrate levels, indictated a normal pituitary response to androgen deprivation. Whilst no change in prolactin was observed, serum FSH showed a biphasic increase which is discussed in relation to the spermatogenic process.Keywords
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