Increased skin lactate in complex regional pain syndrome: Evidence for tissue hypoxia?
- 24 October 2000
- journal article
- Published by Wolters Kluwer Health in Neurology
- Vol. 55 (8), 1213-1215
- https://doi.org/10.1212/wnl.55.8.1213
Abstract
Article abstract To investigate oxygen metabolism in complex regional pain syndrome (CRPS), the authors measured skin lactate via dermal microdialysis performed on patients with CRPS (n = 11) and healthy control subjects (n = 11). In addition, they measured blood lactate. Although venous lactate was unaltered, skin lactate was increased in patients with CRPS (2.95 mmol/L; control subjects 1.74 mmol/L; p < 0.005). These results suggest enhanced anaerobic glycolysis, probably as a result of chronic tissue hypoxia.Keywords
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