Telomeric site position heterogeneity in macronuclear DNA ofParamecium primaurelia
Open Access
- 25 February 1987
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 15 (4), 1717-1728
- https://doi.org/10.1093/nar/15.4.1717
Abstract
In Paramecium primaurelia , the macronuclear gene encoding the G surface protein is located near a telomere. In this study, multiple copies of this telomere have been isolated and the subtelomeric and telomeric regions of some of them have been sequenced. The telomeric sequences consist of tandem repeats of the hexanucleotides C 4 A 2 or C 3 A 3 . We show that the location where these repeats are added, which we call the telomeric site, is variable within a 0.6–0.8-kb region. These results are discussed in relation with the formation of macronuclear DNA.Keywords
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