The influence of temperature on the tension developed in an isometric twitch

Abstract

In muscular contraction the development of tension requires that the contractile component should shorten and stretch the series elastic component. In an isometric twitch the maximum tension is reached as a balance between two opposing processes, internal shortening on the one hand and decay of the active state (relaxation) on the other. The fact that the maximum tension in a twitch is considerably less than in a tetanus has been attributed to oncoming relaxation allowing insufficient time for internal shortening to be completed. The maximum tension in a twitch is considerably reduced by a rise of temperature, while that in a tetanus is somewhat increased. This would require that the temperature coefficient of the velocity of shortening should be substantially less than that of the decay of activity. Evidence for this exists. On this view the effect of a quick stretch, applied during the early stage of a twitch, in increasing the tension ratio, stretch/isometric, should be much greater at a higher temperature. This expectation is confirmed on frogs' muscles over the range 0 to 20 degrees C. The effect of temperature, therefore, on the size of a twitch can be attributed to the difference between the temperature coefficients of velocity of shortening and rate of relaxation.