Review article: a role for gastrointestinal prokinetic agents in the treatment of reflux oesophagitis?
- 1 April 1989
- journal article
- review article
- Published by Wiley in Alimentary Pharmacology & Therapeutics
- Vol. 3 (2), 113-131
- https://doi.org/10.1111/j.1365-2036.1989.tb00197.x
Abstract
Gastro-oesophageal reflux disease may result from a host of factors. Medical therapy has largely been aimed at neutralizing acid or decreasing acid production but improvement of upper-gastrointestinal motility may prove to be a valuable treatment modality as well. This paper reviews the current state of knowledge of the pathogenesis of reflux disease and concentrates upon promotility treatment with domperidone, metoclopramide and cisapride.Keywords
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