Radioautographic study of 5-hydroxytryptamine-containing nerve terminals in central ganglia ofPlanorbis corneus: comparison with other species and characteristics of the serotoninergic nerve terminal
- 1 August 1978
- journal article
- research article
- Published by Springer Nature in Journal of Neurocytology
- Vol. 7 (4), 443-459
- https://doi.org/10.1007/bf01173990
Abstract
Central ganglia fromPlanorbis corneus were incubated with [3H] 5-hydroxytryptamine and [3H]-leucine. After fixation, sections were examined by light and electron microscopic autoradiography. With [3H] 5-hydroxytryptamine there was a high level of uptake into a small number of axons and terminal processes in the neuropil. The terminal processes contained granular vesicles (diameter 50–120 nm), some of which possessed eccentrically placed cores, and agranular vesicles (mean diameter 60 nm). No membrane synaptic specializations were observed. With [3H] leucine there was a general distribution of radioactivity throughout the ganglia. The vesicular inclusions and non-specialized nature of the labelled terminal processes were very similar to presumed 5-hydroxytryptamine-containing terminals in other invertebrates and in the mammalian brain. It appears that several anatomical features of serotoninergic nerve terminals are common in all animals studied, although there is no specific characteristic which allows positive identification.This publication has 35 references indexed in Scilit:
- Radioautographic study of in vivo incorporation of3H-monoamines in the cat caudate nucleus: Identification of serotoninergic fibersBrain Research, 1976
- Axonal transport of [3H]serotonin in an identified neuron of Aplysia californica.The Journal of cell biology, 1976
- Serotonin axons in the supra- and subependymal plexuses and in the leptomeninges; Their roles in local alterations of cerebrospinal fluid and vasomotor activityBrain Research, 1976
- Serotonin nerve terminals in adult rat neocortexBrain Research, 1975
- Monoamine oxidase activity inHelix pomatiaCellular and Molecular Life Sciences, 1975
- Demonstration of indolaminergic fibres in the median eminence of the duck, rat and monkeyNature, 1974
- Chemical transmission in invertebrate central nervous systems and neuromuscular junctions.Physiological Reviews, 1973
- Subcellular Localization of Serotonin in an Identified Serotonin-containing NeuroneNature, 1970
- Radioisotopic studies of the binding, exchange, and distribution of 5-hydroxytryptamine synthesized from its radioactivity precursorThe Journal of Physiology, 1966
- HIGH-RESOLUTION AUTORADIOGRAPHYThe Journal of cell biology, 1962