Genetic analysis of human salivary ?-amylase isozymes by isoelectric focusing
- 1 December 1981
- journal article
- research article
- Published by Springer Nature in Biochemical Genetics
- Vol. 19 (11-12), 1055-1062
- https://doi.org/10.1007/bf00484564
Abstract
The isozymes of human salivary α-amylase have been separated by thin-layer gel isoelectric focusing in a pH 4–8 gradient followed by a starch-iodine zymogram procedure. The normal isozyme pattern (N) consisted of five major isozymes together with a number of minor ones. In addition, seven variant isozyme phenotypes were also observed, which had a combined frequency of 11.7% in a random population of 368 individuals. Analysis of familial data is indicative of the inheritance of autosomal codominant alleles.Keywords
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