INSULIN, MAST CELL COMPONENTS, AND "ANAPHYLACTOID" INFLAMMATION
- 1 May 1958
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry and Physiology
- Vol. 36 (5), 483-489
- https://doi.org/10.1139/o58-054
Abstract
The treatment of rats with an antihistaminic, or a long pretreatment with a histamine depletor, inhibits the "anaphylactoid" inflammation, and inhibits the sensitizing effect of insulin on this inflammation. However, the systemic administration of histamine, serotonin, and heparin does not restore the inhibited "anaphylactoid" inflammation, and does not restore the sensitizing effect of insulin. The three substances administered systemically are also unable to imitate, in normal rats, the sensitizing effect of insulin.Keywords
This publication has 4 references indexed in Scilit:
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- 5-Hydroxytryptamine in Mast Cells.Experimental Biology and Medicine, 1955
- ANTIPHLOGISTIC EFFECT OF TRYPSIN IN NORMAL AND IN ADRENALECTOMIZED RATSCanadian Journal of Biochemistry and Physiology, 1955
- Protamine-like Property of Compounds 48/80 and Stilbamidine and Their Action on Mast Cells.Experimental Biology and Medicine, 1953