Adenylyl cyclase, G proteins, and synaptic plasticity
- 1 September 1995
- journal article
- Published by Cambridge University Press (CUP) in Behavioral and Brain Sciences
- Vol. 18 (3), 484-485
- https://doi.org/10.1017/s0140525x00039418
Abstract
It has been suggested that type I adenylyl cyclase may play a unique role in long-term potentiation, due to both unique regulatory properties as well as a specialized distribution within the mammalian brain. This would allow an integration of the signals wrought by increased intracellular calcium with those conveyed into the cellular milieu via increased cAMP. These results are discussed in the context of changes in cellular structure, because of changing interactions between G proteins and cytoskeletal components, which might be expected to accompany chronic synaptic activation.Keywords
This publication has 729 references indexed in Scilit:
- Inhibition of Rhodopsin Phosphorylation by Non-Myristoylated Recombinant RecoverinBiochemical and Biophysical Research Communications, 1994
- Rhodopsin′s Secondary Structure Revisited: Assignment of Structural ElementsBiochemical and Biophysical Research Communications, 1994
- Two new rhodopsin transversion mutations (L40R; M216K) in families with autosomal dominant retinitis pigmentosaHuman Mutation, 1994
- A leucine to arginine amino acid substitution at codon 46 of rhodopsin is responsible for a severe form of autosomal dominant retinitis pigmentosaHuman Mutation, 1993
- In vivo farnesylation of rat rhodopsin kinaseBiochemical and Biophysical Research Communications, 1992
- Glutamate triggers internucleosomal DNA cleavage in neuronal cellsBiochemical and Biophysical Research Communications, 1991
- Cytosolic free magnesium in cardiac myocytes: Identification of a Mg 2+ influx pathwayBiochemical and Biophysical Research Communications, 1990
- All E‐10,20‐methanoretinoylopsin, light‐stable rhodopsin. Synthesis and spectroscopy of all E‐10,20‐methano‐ and all‐E‐retinoyl fluoride and their reaction with bovine opsinRecueil des Travaux Chimiques des Pays-Bas, 1989
- Retinal rod GTPase turnover rate increases with concentration: A key to the control of visual excitation?Biochemical and Biophysical Research Communications, 1987
- Light dissociates enzymatically-cleaved rhodopsin into two different fragmentsJournal of Molecular Biology, 1975