MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets
Top Cited Papers
Open Access
- 4 September 2007
- journal article
- review article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 117 (9), 2369-2376
- https://doi.org/10.1172/jci33099
Abstract
MicroRNAs act as negative regulators of gene expression by inhibiting the translation or promoting the degradation of target mRNAs. Recent studies have revealed key roles of microRNAs as regulators of the growth, development, function, and stress responsiveness of the heart, providing glimpses of undiscovered regulatory mechanisms and potential therapeutic targets for the treatment of heart disease.This publication has 67 references indexed in Scilit:
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