Catabolism of Cholesterol by Bovine Adrenal-Cortex Enzymes: in vitro Formation of Oxygenated Sterols and Side-Chain Cleavage Products
- 1 April 1976
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 63 (2), 491-497
- https://doi.org/10.1111/j.1432-1033.1976.tb10252.x
Abstract
The identification of sterols and steroids formed by incubation of [7.alpha.-3H, 26-14C]cholesterol with mitochondrial enzymes from bovine adrenal cortex is reported. Only 17% of the radioactivity associated with cholesterol metabolites was in pregnenolone, whereas 15% was reliable to oxygenated sterols and 6% to steroid compounds. The significance of the formation of these compounds is discussed particularly as regards oxygenated cholesterol derivatives.This publication has 14 references indexed in Scilit:
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