The permeability transition pore signals apoptosis by directing Bax translocation and multimerization
Open Access
- 25 February 2002
- journal article
- fj express-summaries
- Published by Wiley in The FASEB Journal
- Vol. 16 (6), 607-609
- https://doi.org/10.1096/fj.01-0269fje
Abstract
Mitochondria are key players of apoptosis and can irreversibly commit the cell to death by releasing cytochrome c (Cyt.c) to the cytosol, where caspases 9 and 3 subsequently get activated. Under cond...Keywords
Funding Information
- Institut National de la Santé et de la Recherche Médicale
- Association pour la Recherche sur le Cancer
- Conseil Régional Aquitaine
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