SEVERE GENERALIZED BLASTOMYCETIC DERMATITIS

Abstract

In May 1894 Gilchrist examined sections in which he first found blastomycetes. In November 1894 Busse¹reported a case of systemic blastomycosis in which the diagnosis was confirmed by postmortem examination. In 1896 Gilchrist and Stokes²reported a case of chronic cutaneous oidium infection. The causative organism was found in pus and in sections of tissue. Inoculations of animals with fresh tissue gave negative results. The cultural characteristics of the organism were described, and in a subsequent report, in 1896,³this case was definitely classified as one of cutaneous blastomycosis. Since its recognition many therapeutic agents have been used in the treatment of the disease, and iodides have held a prominent place among these agents. Little attention has been given to the use of intravenous injections of compound solution of iodine U. S. P., as suggested by Ravaut,⁴in the treatment of this and other mycotic