To explore digestive system manifestations in patients with severe acute respiratory syndrome (SARS). The clinical data of 96 cases with SARS admitted into our hospital from February 6, 2003 to March 28, 2003 were retrospectively analyzed. Among the 96 cases, 26 cases (27%) had diarrhea, 17 (18%) had nausea, 6 (6%) had vomiting, 16 (17%) had bellyache, and 8 (8%) had ALT elevation. Patients with SARS may have digestive system manifestations; diarrhea is the most common symptom.