The Effect of Exercise on Coronary Blood Flow, Myocardial Oxygen Consumption and Cardiac Efficiency in Man
- 1 January 1953
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 7 (1), 71-78
- https://doi.org/10.1161/01.cir.7.1.71
Abstract
It has been known that exercise causes an increase in the coronary blood flow in animals. The present work has been carried out to study the effect of exercise on coronary blood flow and myocardial oxygen consumption of the human heart in vivo. The results indicate that the heart responds to the increased load of exercise with a rise in coronary blood flow. Since the arteriovenous coronary oxygen difference shows little change, the increase in oxygen consumption of the heart muscle is primarily the result of an increased coronary blood flow. As the cardiac work rises more than the myocardial oxygen consumption, the left ventricular efficiency increases. The response of the failing heart muscle to acute increases in load produced by exercise does not differ from that of the normal heart or of the isolated heart.Keywords
This publication has 23 references indexed in Scilit:
- A COMPLICATION FOLLOWING CORONARY SINUS AND CARDIAC VEIN CATHETERIZATION IN MANHeart, 1951
- Behavior of the myocardium in health and disease as studied by coronary sinus catheterizationAmerican Journal Of Medicine, 1951
- The measurement of coronary blood flow, oxygen consumption, and efficiency of the left ventricle in manAmerican Heart Journal, 1949
- ESSENTIAL HYPERTENSIONJAMA, 1949
- EFFECT OF EXERCISE ON CARDIAC OUTPUT AND PULMONARY ARTERIAL PRESSURE IN NORMAL PERSONS AND IN PATIENTS WITH CARDIOVASCULAR DISEASE AND PULMONARY EMPHYSEMA 1JCI Insight, 1948
- THE ESTIMATION OF HEPATIC BLOOD FLOW IN MANJCI Insight, 1945
- Catheterization of the Right Auricle in ManExperimental Biology and Medicine, 1941
- THE NATURE OF THE PERIPHERAL RESISTANCE IN ARTERIAL HYPERTENSION WITH SPECIAL REFERENCE TO THE VASOMOTOR SYSTEMJCI Insight, 1936
- The relation of the weight of the heart to the weight of the body and of the weight of the heart to ageAmerican Heart Journal, 1928
- The regulation of the energy output of the heartThe Journal of Physiology, 1927