Genetic Heterogeneity of Dominant Optic Atrophy, Kjer Type

Abstract
AUTOSOMAL dominant optic atrophy (Mendelian Inheritance in Man 165500 1) is a hereditary disorder characterized by bilateral insidious onset of vision loss, dyschromatopsia, central visual field defects, and optic nerve pallor.2-5 The gene is highly penetrant and has variable expressivity.