Polypeptide Transforming Growth Factors Isolated from Bovine Sources and Used for Wound Healing in Vivo
- 18 March 1983
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 219 (4590), 1329-1331
- https://doi.org/10.1126/science.6572416
Abstract
Transforming growth factors, which are polypeptides that induce the transformed phenotype in nonneoplastic cells, have been isolated in bulk amounts from bovine salivary gland and kidney. In experiments in which wound healing chambers were implanted subcutaneously in the backs of rats, these bovine transforming growth factors accelerated the accumulation of total protein, collagen, and DNA in treated chambers. These studies thus show an effect of an isolated transforming growth factor in vivo.This publication has 17 references indexed in Scilit:
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