Breast Cancer Diagnosis and Prognosis through Quantitative Measurements of Serum Glycan Profiles
- 1 July 2008
- journal article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 54 (7), 1166-1175
- https://doi.org/10.1373/clinchem.2007.087148
Abstract
Background: Glycosylated proteins play important roles in cell-to-cell interactions, immunosurveillance, and a variety of receptor-mediated and specific protein functions through a highly complex repertoire of glycan structures. Aberrant glycosylation has been implicated in cancer for many years.Keywords
Funding Information
- National Institutes of Health (GM24349)
- National Center for Research Resources (RR018942)
- National Cancer Institute (R01 CA83199)
This publication has 31 references indexed in Scilit:
- High Throughput Quantitative Glycomics and Glycoform-focused Proteomics of Murine Dermis and EpidermisMolecular & Cellular Proteomics, 2005
- β1,6-Branched Oligosaccharides Are Increased in Lymph Node Metastases and Predict Poor Outcome in Breast CarcinomaClinical Cancer Research, 2005
- Noninvasive diagnosis of liver cirrhosis using DNA sequencer–based total serum protein glycomicsNature Medicine, 2004
- Glycosylation profile of integrin α3β1 changes with melanoma progressionBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2003
- Antibody Domain Exchange Is an Immunological Solution to Carbohydrate Cluster RecognitionScience, 2003
- The Emerging Significance of O-GlcNAc in Cellular RegulationChemical Reviews, 2002
- Glycosylation and the Immune SystemScience, 2001
- Breast cancer progression is associated with a reduction in the diversity of sialylated and neutral oligosaccharidesClinica Chimica Acta; International Journal of Clinical Chemistry, 1998
- Viewing AIDS from a glycobiological perspective: potential linkages to the human fetoembryonic defence system hypothesisMolecular Human Reproduction, 1997
- Analysis of glycoproteins released from benign and malignant human breast: Changes in size and fucosylation with malignancyEuropean Journal of Cancer and Clinical Oncology, 1989