Patients (20) with chronic pain in the right lower quadrant of the abdomen were reviewed for preoperative findings and pathologic findings at laparotomy. Of the 20 patients, 11 had acute appendicitis and 13 of the 20 had some appendiceal problem. The WBC count was not reliable in diagnosing this since 8 of the 11 with acute appendicitis had a normal WBC count. Ba enema examination was performed in 10 of the 13 with disease, and abnormalities were noted in 9 of the 10, an indication of a high degree of reliability of this examination. Long term follow-up study revealed that 17 of the patients in the study gained complete relief of symptoms after appendectomy.